Multi-gene analysis

Welcome to gene.iobio.
A tool for disease-causing variant discovery & interrogation
  • On the fly annotation
    • Functional impact (e.g. VEP, Sift, Polyphen)
    • Allele Frequency (e.g. 1000G, ExAC)
    • Inheritance Mode
  • Visualize Variants and Read Coverage together
  • Analyze Trios and affected/unaffected siblings
  • Instantly analyze VCF and BAM files both on your hard drive or on the web with no need to upload the entire file
Ranked Variants
map Show legend
Evaluate Variants
No clinvar variants under 1% population frequency found
Ranking variants
swap_vert Reorder
More likely causative
Most harmful

shaded columns: flagged for not meeting filtering criteria


Welcome to gene.iobio

An app for interrogating disease-causing variants